Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD
نویسندگان
چکیده
منابع مشابه
Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD
As a member of 18 glycosyl hydrolase (GH) family, chitotriosidase (Chitinase 1, CHIT1) is a true chitinase mainly expressed in the differentiated and polarized macrophages. CHIT1 is an innate immune mediator that digests the cell walls of chitin-containing eukaryotic pathogens, such as fungi. However, CHIT1 is dysregulated in granulomatous and fibrotic interstitial lung diseases characterized b...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Immunology Research
سال: 2015
ISSN: 2092-7355,2092-7363
DOI: 10.4168/aair.2015.7.1.14